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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T8394 | D-Serine | (R)-Serine | Endogenous Metabolite , NMDAR , iGluR |
D-Serine ((R)-Serine) is an endogenous amino acid,is a potent co-agonist at the NMDA glutamate receptor. | |||
T66377 | N-Cbz-D-serine Methyl Ester | ||
N-Cbz-D-serine Methyl Ester is a useful organic compound for research related to life sciences. The catalog number is T66377 and the CAS number is 93204-36-5. | |||
T9143 | D-Isoleucine | (2R,3R)-2-Amino-3-methylpentanoic acid,(R)-Isoleucine | Others |
D-Isoleucine ((2R,3R)-2-Amino-3-methylpentanoic acid) is a selective activator of Asc-1 antiporter, which enhances long-term potentiation at the hippocampal CA1-CA3 via release of endogenous D-serine. | |||
T13568L | BCX 1470 hydrochloride | BCX 1470 hydrochloride(217099-43-9 Free base),BCX1470 HCl | Serine Protease , Complement System |
BCX 1470 hydrochloride is a potent serine protease inhibitor with anti-inflammatory activity that inhibits the ester hydrolysis and haemolytic activity of factor D and C1s, and can be used to study oedema. | |||
T8363 | DL-Serine | PKM | |
DL-Serine is a non-essential amino acid and a natural ligand and allosteric activator of pyruvate kinase M2. | |||
T5085 | Pyridoxal 5'-phosphate hydrate | Codecarboxylase,Pyridoxal 5'-phosphate hydrate(1:x),PLP,Pyridoxal 5'-phosphate hydrate | Others , Endogenous Metabolite |
Pyridoxal 5'-phosphate hydrate (PLP)(1:x), the active form of vitamin B6, is a cofactor for many different enzymes involved in transamination reactions, including mitochondrial cysteine desulfurase, cystathionine γ-synth... | |||
T37185 | D-(-)-3-Phosphoglyceric acid disodium | 3-Phospho-D-glyceric acid disodium | Others |
D-(-)-3-Phosphoglyceric acid disodium (3-Phospho-D-glyceric acid disodium) is an intermediate in several biological pathways, most notably glycolysis/gluconeogenesis and the biosynthesis of serine, glycine, and threonine... | |||
TP1920L1 | Acein acetate | RAAS | |
Acein acetate is a high-affinity angiotensin-converting enzyme (ACE) ligand (Kd = 2.79 nM). Concentrations up to 500 nM had no significant effect on ACE enzyme activity. Enhanced NMDA + D-serine-induced dopamine release ... | |||
T6904 | Necrosulfonamide | (E)-Necrosulfonamide | MLK |
(E)-Necrosulfonamide ((E)-Necrosulfonamide) is an inhibitor of necroptosis. Blocks mixed lineage kinase domain-like protein (MLKL), a critical substrate of receptor-interacting serine-threonine kinase 3 (RIP3) during nec... | |||
T4825 | D-(+)-Xylose | D(+)-Xylose,(+)-Xylose,Wood sugar | Endogenous Metabolite |
D-(+)-Xylose (Wood sugar) is an aldopentose - a monosaccharide containing five carbon atoms and an aldehyde functional group. It has chemical formula C5H10O5 and is 40% as sweet as sucrose. Xylose is also found in mucopo... | |||
T32853 | Lombricine | L-Lombricine | |
Lombricine, as a phosphodiester of 2-guanidinoethanol and D-serine in structure, is a phosphagen that is unique to earthworms. | |||
T36396 | D-Homoserine lactone | ||
D-homoserine lactone is an enantiomer of L-homoserine lactone and an inhibitor of serine hydroxymethyltransferase (SHMT; Ki= 11 mM for the rabbit enzyme).1 1.Wang, E.A., Kallen, R., and Walsh, C.Mechanism-based inactivat... | |||
T76170 | D-Amino acid oxidase | ||
D-Amino acid oxidase, an enzyme that metabolizes exogenous D-amino acids in animals for detoxification, also regulates the level of D-serine in the brain [1]. | |||
T74145 | Deutarserine | ||
Deutarserine, a deuterium-modified analog of the endogenous compound D-serine (CTP 692), is utilized in schizophrenia research in adults [1]. | |||
T78231 | DAO-IN-1 | Others | |
DAO-IN-1 is a potent D-amino acid oxidase (DAO) inhibitor, exhibiting an IC50 of 269 nM, which plays a key role in the metabolism of D-serine, a co-agonist of NMDA receptors [1]. | |||
TP1920 | Acein | ||
Acein is a High affinity angiotensin-converting enzyme (ACE) ligand (Kd = 2.79 nM). Exhibits no significant effect on ACE enzymatic activity up to 500 nM concentration. Potentiates NMDA + D-serine-induced dopamine releas... | |||
T10939 | D,L-Cystathionine dihydrochloride | Others | |
D,L-Cystathionine dihydrochloride is an intermediate in the synthesis of cysteine, which acts from the isotype of cysteine-β-synthase (CBS) produced by leucine and serine. Derived from cysteine. DL-cysteine contains a cy... | |||
T11269 | FD-IN-1 | Others | |
FD-IN-1 is a factor D (FD) inhibitor with an IC50 of 12 nM.FD-IN-1 also inhibits factor XIa (FXIa) and Tryptase β2 with IC50s of 7.7 and 6.5μM, respectively. Complement FD, a highly specific S1 serine protease, plays a... | |||
T37056 | D-erythro-MAPP | ||
D-erythro-MAPP is a derivative of ceramide and an inhibitor of alkaline ceramidase (Ki = 2-13 μM; IC50 = 1-5 μM). It is selective for alkaline ceramidase over acid ceramidase (IC50 = >500 μM) as well as the serine/threon... | |||
T36643 | PKI-166 hydrochloride | ||
Potent EGFR-kinase inhibitor (IC50 = 0.7 nM). Displays >3000-fold selectivity against a panel of serine/threonine kinases. Reduces metastasis and angiogenesis in a mouse model of pancreatic cancer. Antihypertensive and o... |